Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4,6-Dichloro-5-fluoropyrimidin-2-amine

  • CAS No. 15598-33-1

  • Cat. No. CS-0109987
  • Purity≥95%
  • MDL No.MFCD11870221

*For research and further manufacturing use only, not for direct human use.

4,6-Dichloro-5-fluoropyrimidin-2-amine|CS-0109987

Structure of 15598-33-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 15598-33-1
  • Cat. No. CS-0109987
  • Purity ≥95%
  • MDL No. MFCD11870221
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂Cl₂FN₃
  • Molecular Weight 181.98
  • Synonym(s) 4,6-Dichloro-5-fluoro-pyrimidin-2-ylamine
  • SMILES NC1=NC(Cl)=C(F)C(Cl)=N1

Description

4,6-Dichloro-5-fluoropyrimidin-2-amine features a highly reactive pyrimidine core with orthogonal halogen substituents enabling selective cross-coupling. The electron-deficient ring facilitates nucleophilic substitution under mild conditions, while the amino group serves as a direct handle for derivatization in medicinal chemistry and agrochemical synthesis.

Application

4,6-Dichloro-5-fluoropyrimidin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of kinase inhibitors and antiviral agents. Its electrophilic pyrimidine core undergoes facile nucleophilic substitution with amines, thiols, and heterocycles under mild conditions. The dichloro and fluoro substituents provide orthogonal reactivity for sequential functionalization, while the amine group offers a handle for further derivatization. Bench-stable and readily purified by recrystallization, it is well-suited for scale-up and high-throughput synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.5047
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4,6-Dichloro-5-fluoropyrimidin-2-amine sigma4,6-Dichloro-5-fluoropyrimidin-2-amine manufacturer4,6-Dichloro-5-fluoropyrimidin-2-amine price4,6-Dichloro-5-fluoropyrimidin-2-amine structure4,6-Dichloro-5-fluoropyrimidin-2-amine SDSbuy 4,6-Dichloro-5-fluoropyrimidin-2-amine4,6-Dichloro-5-fluoropyrimidin-2-amine supplier4,6-Dichloro-5-fluoropyrimidin-2-amine uses4,6-Dichloro-5-fluoropyrimidin-2-amine molecular weightprice of 4,6-Dichloro-5-fluoropyrimidin-2-amine4,6-Dichloro-5-fluoropyrimidin-2-amine chemical name formula of 4,6-Dichloro-5-fluoropyrimidin-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label