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Structure of 1558302-68-3
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6-Chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine features a chlorinated pyrazolopyridine core with enhanced electron-deficient character, enabling efficient coupling in cross-coupling reactions. The methyl group at the 1-position improves solubility and stability under standard conditions, while the chlorine serves as a reactive handle for palladium-catalyzed transformations. This scaffold integrates readily into complex heterocyclic architectures.
6-Chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to substituted pyrazolopyridines via palladium-catalyzed cross-coupling reactions. Its chlorine atom facilitates nucleophilic substitution under mild conditions, while the methyl group enhances solubility and metabolic stability. The scaffold exhibits excellent bench stability and compatibility with standard reaction workflows, making it ideal for rapid library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: