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CS-W001157 4
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3-(Pyridin-2-yl)propan-1-amine

  • CAS No. 15583-16-1

  • Cat. No. CS-0006435
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD06809629

*For research and further manufacturing use only, not for direct human use.

3-(Pyridin-2-yl)propan-1-amine|CS-0006435

Structure of 15583-16-1

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General Information

  • CAS No. 15583-16-1
  • Cat. No. CS-0006435
  • Purity ≥97%
  • MDL No. MFCD06809629
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight None
  • Synonym(s) 3-PYRIDIN-2-YL-PROPYLAMINE
  • SMILES NCCCC1=NC=CC=C1

Description

3-(Pyridin-2-yl)propan-1-amine features a pyridine ring linked via a propyl chain to a primary amine, delivering a rigid, electron-deficient heteroaromatic handle. This structure enables direct incorporation into ligands and catalyst scaffolds, offering enhanced solubility and directional binding in coordination chemistry applications.

Application

3-(Pyridin-2-yl)propan-1-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds through amine functionalization. Its pyridyl moiety provides strong coordination potential and enhanced solubility, while the primary aliphatic amine facilitates straightforward derivatization via acylation, alkylation, or reductive amination. The compound exhibits good bench stability and ease of purification, making it well-suited for scalable synthesis and process development.

Synthesis

  • Route1
    • null|null
      838892-94-7
    • ~86%
    • In-stock
      3-(Pyridin-2-yl)propan-1-amine|CS-0006435
      15583-16-1

    References

    • Geyer, Roland; Igel, Patrick; Kaske, Melanie; Elz, Sigurd; Buschauer, Armin MedChemComm, 2014 , vol. 5, # 1 p. 72 - 81
  • Route2
    • null|null
      100-69-6
    • ~%
    • In-stock
      3-(Pyridin-2-yl)propan-1-amine|CS-0006435
      15583-16-1

    References

    • US2003/105132 A1, ; US 20030105132 A1
  • Route3
    • null|null
      2859-68-9
    • ~%
    • In-stock
      3-(Pyridin-2-yl)propan-1-amine|CS-0006435
      15583-16-1

    References

    • Heterocycles, , vol. 66, # 1 p. 161 - 166

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.9729
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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