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CS-W001157 4
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3-Methoxybenzenethiol

  • CAS No. 15570-12-4

  • Cat. No. CS-0008476
  • Purity≥98%
  • MDL No.MFCD00004841

*For research and further manufacturing use only, not for direct human use.

3-Methoxybenzenethiol|CS-0008476

Structure of 15570-12-4

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General Information

  • CAS No. 15570-12-4
  • Cat. No. CS-0008476
  • Purity ≥98%
  • MDL No. MFCD00004841
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈OS
  • Molecular Weight None
  • Synonym(s) m-Methoxybenzenethiol; m-Methoxythiophenol; 3-Methoxythiophenol
  • SMILES SC1=CC=CC(OC)=C1

Description

3-Methoxythiophenol was used in the preparation of allenes.

Application

3-Methoxybenzenethiol serves as a versatile building block in medicinal chemistry and materials science, enabling the construction of sulfide-linked heterocycles and functionalized aromatic systems. Its thiol group facilitates reliable conjugation reactions, while the ortho-methoxy substituent enhances solubility and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with standard protecting group strategies, making it well-suited for multi-step synthesis and process-scale applications.

Synthesis

  • Route1

    References

    • Jiang, Yongwen; Qin, Yuxia; Xie, Siwei; Zhang, Xiaojing; Dong, Jinhua; Ma, Dawei Organic Letters, 2009 , vol. 11, # 22 p. 5250 - 5253
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      3-Methoxybenzenethiol|CS-0008476
      15570-12-4

    References

    • Chemische Berichte, , vol. 106, p. 2419 - 2426
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    References

    • Journal of Medicinal Chemistry, , vol. 18, p. 921 - 925

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: 3334
Class : 9
Packing Group : Ⅲ
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   1.9839
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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