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CS-W001157 4
Total: USD 88.00

4,7-Dimethylindoline-2,3-dione

  • CAS No. 15540-90-6

  • Cat. No. CS-0074420
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4,7-Dimethylindoline-2,3-dione|CS-0074420

Structure of 15540-90-6

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General Information

  • CAS No. 15540-90-6
  • Cat. No. CS-0074420
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO₂
  • Molecular Weight 175.18
  • Synonym(s) 4,7-dimethyl-1H-indole-2,3-dione
  • SMILES O=C(C1=O)NC2=C1C(C)=CC=C2C

Description

4,7-Dimethylindoline-2,3-dione is a sterically hindered, bench-stable diketopiperazine derivative featuring electron-deficient aromatic cores. This compound integrates readily into synthetic sequences requiring robust heterocyclic scaffolds under standard conditions. Its methyl substitution pattern enhances solubility and stability in polar aprotic solvents, enabling efficient incorporation into complex molecular architectures.

Application

4,7-Dimethylindoline-2,3-dione serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted indole and isoindolinone scaffolds. Its electron-deficient quinone core facilitates Diels-Alder reactions and nucleophilic additions, while the methyl groups enhance solubility and stability under standard reaction conditions. The compound exhibits excellent functional group tolerance and is readily purified by flash chromatography, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319-H413
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.17
  • LogP   1.43824
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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