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CS-W001157 4
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3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoic acid

  • CAS No. 155369-11-2

  • Cat. No. CS-0169151
  • Purity≥98%
  • MDL No.MFCD00273463

*For research and further manufacturing use only, not for direct human use.

3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoic acid|CS-0169151

Structure of 155369-11-2

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General Information

  • CAS No. 155369-11-2
  • Cat. No. CS-0169151
  • Purity ≥98%
  • MDL No. MFCD00273463
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₁₉NO₄
  • Molecular Weight 373.40
  • Synonym(s) Fmoc-3-Aminomethylbenzoic acid
  • SMILES O=C(O)C1=CC=CC(CNC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)=C1

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a robust C-terminal carboxyl group and a stable fluoren-9-ylmethoxy carbonyl (Fmoc) handle, enabling efficient solid-phase peptide synthesis. The ortho-substituted benzoic acid moiety enhances solubility and facilitates purification. Designed for high-yield coupling reactions under standard conditions.

Synthesis

  • Route1
    • 3-(Aminomethyl)benzoic acid|CS-0449925
      2393-20-6
    • In-stock
      Fmoc-Osu Amino acid impurity|CS-1733136
      82911-69-1
    • ~65%
    • In-stock
      3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)benzoic acid|CS-0169151
      155369-11-2

    References

    • Smythe; Von Itzstein Journal of the American Chemical Society, 1994 , vol. 116, # 7 p. 2725 - 2733

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.4235
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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