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CS-W001157 4
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Methyl indoline-4-carboxylate

  • CAS No. 155135-61-8

  • Cat. No. CS-0141055
  • Molecule weight177.20
  • Purity≥95%
  • MDL No.MFCD07371619

*For research and further manufacturing use only, not for direct human use.

Methyl indoline-4-carboxylate|CS-0141055

Structure of 155135-61-8

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General Information

  • CAS No. 155135-61-8
  • Cat. No. CS-0141055
  • Purity ≥95%
  • MDL No. MFCD07371619
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁NO₂
  • Molecular Weight 177.20
  • Synonym(s) Methyl 2,3-dihydro-1H-indole-4-carboxylate
  • SMILES O=C(C1=CC=CC2=C1CCN2)OC

Description

Methyl indoline-4-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a fused indoline core with a strategically positioned ester group. This scaffold integrates readily into synthetic sequences requiring electron-rich aromatic systems and enables direct functionalization at the 4-position.

Application

Methyl indoline-4-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient construction of indoline-based scaffolds prevalent in bioactive molecules. Its carboxylate functionality facilitates direct amidation, reduction, and metal-catalyzed coupling reactions. The indoline core exhibits excellent bench stability and compatibility with diverse functional groups, simplifying purification and scale-up. This compound functions reliably in standard synthetic workflows for targeted heterocycle elaboration.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.4412
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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