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CS-W001157 4
Total: USD 88.00

2-Bromo-6-fluoro-3-methylbenzaldehyde

  • CAS No. 154650-16-5

  • Cat. No. CS-W006422
  • Purity≥96%
  • MDL No.MFCD11520666

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-fluoro-3-methylbenzaldehyde|CS-W006422

Structure of 154650-16-5

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General Information

  • CAS No. 154650-16-5
  • Cat. No. CS-W006422
  • Purity ≥96%
  • MDL No. MFCD11520666
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrFO
  • Molecular Weight 217.04
  • Synonym(s) None
  • SMILES O=CC1=C(F)C=CC(C)=C1Br

Description

2-Bromo-6-fluoro-3-methylbenzaldehyde features a trifunctional aromatic core with bromo, fluoro, and methyl groups positioned for orthogonal reactivity. The aldehyde moiety enables direct coupling or functionalization in synthetic sequences. This electron-deficient benzaldehyde offers enhanced stability under standard conditions and facilitates selective transformations in medicinal chemistry and agrochemical development.

Application

2-Bromo-6-fluoro-3-methylbenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling the construction of substituted aromatic scaffolds via palladium-catalyzed cross-coupling reactions. The ortho-bromo and meta-fluoro substituents provide orthogonal reactivity for sequential functionalization, while the aldehyde group facilitates imine formation, reductive amination, and derivatization. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step syntheses requiring precise regiocontrol.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.70912
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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