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CS-W001157 4
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2,5-Bis(prop-2-yn-1-yloxy)terephthalaldehyde

  • CAS No. 1538579-23-5

  • Cat. No. CS-0110688
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,5-Bis(prop-2-yn-1-yloxy)terephthalaldehyde|CS-0110688

Structure of 1538579-23-5

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General Information

  • CAS No. 1538579-23-5
  • Cat. No. CS-0110688
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₀O₄
  • Molecular Weight 242.23
  • Synonym(s) 2,5-Bis(2-propynyloxy)terephthalaldehyde
  • SMILES O=CC1=CC(OCC#C)=C(C=C1OCC#C)C=O

Description

2,5-Bis(prop-2-yn-1-yloxy)terephthalaldehyde features two propargyloxy groups flanking a central terephthaldehyde core, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and materials assembly. The aldehyde functionality supports orthogonal coupling strategies in complex molecular architectures.

Application

2,5-Bis(prop-2-yn-1-yloxy)terephthalaldehyde serves as a versatile bifunctional building block for the synthesis of complex heterocyclic scaffolds and conjugated systems. The aldehyde groups enable efficient imine formation and reductive amination, while the propargyloxy functionalities offer orthogonal protection and compatibility with CuAAC click chemistry. Its bench-stable nature and high functional group tolerance facilitate reliable use in multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.3356
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   6

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