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CS-W001157 4
Total: USD 88.00

Diclofenac amide

  • CAS No. 15362-40-0

  • Cat. No. CS-0144094
  • Purity≥98%
  • MDL No.MFCD00451393

*For research and further manufacturing use only, not for direct human use.

Diclofenac amide|CS-0144094

Structure of 15362-40-0

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General Information

  • CAS No. 15362-40-0
  • Cat. No. CS-0144094
  • Purity ≥98%
  • MDL No. MFCD00451393
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₉Cl₂NO
  • Molecular Weight 278.14
  • Synonym(s) None
  • SMILES O=C1N(C2=C(Cl)C=CC=C2Cl)C3=C(C=CC=C3)C1

Description

.

Application

Diclofenac amide serves as a stable, bench-ready building block for the synthesis of diclofenac-derived bioactive compounds. Its amide functionality provides enhanced metabolic stability and facilitates downstream functionalization via standard amidation or reduction protocols. The molecule exhibits good solubility in common organic solvents and is compatible with diverse reaction conditions, enabling efficient incorporation into pharmaceutical scaffolds and heterocyclic systems.

Synthesis

  • Route1

    References

    • Moser; Sallmann; Wiesenberg Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2358 - 2368
  • Route2

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2009/16118 A1, 2009 ; Location in patent: Page/Page column 40-41 ;
  • Route3
    • null|null
      83281-94-1
    • ~99%
    • In-stock
      Diclofenac amide|CS-0144094
      15362-40-0

    References

    • Tamura; Uenishi; Choi; et al. Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 5 p. 1995 - 1997

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.31
  • LogP   4.2142
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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