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CS-W001157 4
Total: USD 88.00

(S-methylsulfonimidoyl)methane

  • CAS No. 1520-31-6

  • Cat. No. CS-W000747
  • Molecule weight93.15
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S-methylsulfonimidoyl)methane|CS-W000747

Structure of 1520-31-6

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General Information

  • CAS No. 1520-31-6
  • Cat. No. CS-W000747
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₇NOS
  • Molecular Weight 93.15
  • Synonym(s) S,S-Dimethyl sulfoximine
  • SMILES CS(C)(=N)=O

Description

S-methylsulfonimidoyl)methane features a unique sulfonimidoyl functional group that enables direct incorporation into bioactive molecules. This bench-stable, moisture-tolerant reagent facilitates efficient nitrogen transfer in synthetic transformations, offering enhanced selectivity in amine derivatization and heterocycle construction under mild conditions.

Application

(S-Methylsulfonimidoyl)methane serves as a versatile building block for sulfonimidamide-containing scaffolds, enabling direct access to nitrogen-functionalized heterocycles via standard coupling and cyclization protocols. Its bench-stable nature and tolerance to diverse reaction conditions facilitate efficient synthesis of medicinally relevant motifs in medicinal chemistry workflows.

Synthesis

  • Route1

    References

    • BAYER SCHERING PHARMA AKTIENGESELLSCHAFT; BAYER HEALTHCARE AG Patent: WO2008/141843 A1, 2008 ; Location in patent: Page/Page column 31 ; WO 2008/141843 A1
  • Route2
    • null|null
      21865-94-1
    • ~62%
    • In-stock
      (S-methylsulfonimidoyl)methane|CS-W000747
      1520-31-6

    References

    • Siu, Tung; Yudin, Andrei K. Organic Letters, 2002 , vol. 4, # 11 p. 1839 - 1842
  • Route3

    References

    • Laughlin,R.G.; Yellin,W. Journal of the American Chemical Society, 1967 , vol. 89, p. 2435 - 2443

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P271-P280

Quality Control

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Computational Chemistry Data

  • TPSA   40.92
  • LogP   0.29277
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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