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CS-W001157 4
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4-(2-Carboxyethyl)benzoic Acid Methyl Ester

  • CAS No. 151937-09-6

  • Cat. No. CS-0150811
  • Purity≥96%
  • MDL No.MFCD12406797

*For research and further manufacturing use only, not for direct human use.

4-(2-Carboxyethyl)benzoic Acid Methyl Ester|CS-0150811

Structure of 151937-09-6

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General Information

  • CAS No. 151937-09-6
  • Cat. No. CS-0150811
  • Purity ≥96%
  • MDL No. MFCD12406797
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂O₄
  • Molecular Weight 208.21
  • Synonym(s) 3-[4-(Methoxycarbonyl)phenyl]propanoic acid
  • SMILES COC(=O)C1=CC=C(C=C1)CCC(=O)O

Description

This methyl ester derivative of 4-(2-carboxyethyl)benzoic acid features a pendant carboxylate group ideal for bioconjugation and polymer functionalization. The aromatic core provides rigidity, while the ester linkage enables selective hydrolysis under physiological conditions. Bench-stable and moisture-tolerant, it facilitates efficient coupling in aqueous environments without requiring protective groups.

Application

4-(2-Carboxyethyl)benzoic acid methyl ester serves as a versatile diester building block for the synthesis of functionalized aromatic scaffolds. Its dual carboxylate functionality enables sequential derivatization, while the methyl ester group offers enhanced stability and ease of purification. The molecule facilitates efficient coupling reactions and serves as a key intermediate in the construction of bioactive heterocycles and pharmaceutical candidates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   1.4904
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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