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CS-W001157 4
Total: USD 88.00

3-Hydroxy-2-pyrrolidinone

  • CAS No. 15166-68-4

  • Cat. No. CS-W005201
  • Purity≥98%
  • MDL No.MFCD09751256

*For research and further manufacturing use only, not for direct human use.

3-Hydroxy-2-pyrrolidinone|CS-W005201

Structure of 15166-68-4

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General Information

  • CAS No. 15166-68-4
  • Cat. No. CS-W005201
  • Purity ≥98%
  • MDL No. MFCD09751256
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₂
  • Molecular Weight 101.10
  • Synonym(s) 3-Hydroxy-2-oxo-pyrrolidin
  • SMILES O=C1NCCC1O

Description

3-Hydroxy-2-pyrrolidinone is a polar, bench-stable heterocyclic compound featuring a hydroxyl group at the 3-position and a lactam carbonyl at the 2-position. This structural motif enables efficient integration into peptide mimetics and bioactive molecule scaffolds, offering enhanced solubility and metabolic stability in synthetic workflows.

Application

3-Hydroxy-2-pyrrolidinone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to bioactive heterocycles and pharmaceutical intermediates. Its amide functionality and hydroxyl group offer orthogonal reactivity for selective derivatization, while its inherent stability facilitates handling and purification. This scaffold functions effectively in coupling reactions and cyclization processes, supporting scalable synthesis of complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -1.1328
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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