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CS-W001157 4
Total: USD 88.00

1-Methoxy-4-(methoxymethyl)benzene

  • CAS No. 1515-81-7

  • Cat. No. CS-0150191
  • Purity≥98%
  • MDL No.MFCD00155135

*For research and further manufacturing use only, not for direct human use.

1-Methoxy-4-(methoxymethyl)benzene|CS-0150191

Structure of 1515-81-7

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General Information

  • CAS No. 1515-81-7
  • Cat. No. CS-0150191
  • Purity ≥98%
  • MDL No. MFCD00155135
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₂
  • Molecular Weight 152.19
  • Synonym(s) p-(Methoxymethyl)anisole
  • SMILES COCC1=CC=C(C=C1)OC

Description

1-Methoxy-4-(methoxymethyl)benzene features a para-substituted aromatic core with complementary methoxy and methoxymethyl groups, enabling selective functionalization in synthetic sequences. This electron-rich scaffold offers enhanced solubility and stability under standard conditions, facilitating integration into complex molecular architectures.

Application

1-Methoxy-4-(methoxymethyl)benzene serves as a versatile building block in synthetic organic chemistry, offering orthogonal protection for phenolic and aliphatic hydroxyl groups. Its bench-stable nature and compatibility with standard deprotection protocols facilitate efficient multistep synthesis. The molecule functions as a reliable precursor in the construction of functionalized aromatic scaffolds and heterocycles relevant to medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      4-Methoxybenzyl alcohol|CS-W016493
      105-13-5
    • ~99%
    • In-stock
      1-Methoxy-4-(methoxymethyl)benzene|CS-0150191
      1515-81-7

    References

    • Chavan, Subhash P.; Harale, Kishor R. Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4683 - 4686
  • Route2

    References

    • Torii, Sigeru; Inokuchi, Tsutomu; Takagishi, Sadahito; Horike, Hirofumi; Kuroda, Hideki; Uneyama, Kenji Bulletin of the Chemical Society of Japan, 1987 , vol. 60, p. 2173 - 2188
  • Route3
    • In-stock
      4-Methoxybenzyl alcohol|CS-W016493
      105-13-5
    • null|null
      74-88-4
    • ~95%
    • In-stock
      1-Methoxy-4-(methoxymethyl)benzene|CS-0150191
      1515-81-7

    References

    • Behbahani, Farahnaz K.; Heravi, Majid M.; Oskooie, Hossien A. Monatshefte fur Chemie, 2009 , vol. 140, # 2 p. 181 - 184

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   1.8416
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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