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CS-W001157 4
Total: USD 88.00

3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde

  • CAS No. 151103-09-2

  • Cat. No. CS-W006995
  • Purity≥97%
  • MDL No.MFCD07779381

*For research and further manufacturing use only, not for direct human use.

3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde|CS-W006995

Structure of 151103-09-2

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General Information

  • CAS No. 151103-09-2
  • Cat. No. CS-W006995
  • Purity ≥97%
  • MDL No. MFCD07779381
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂F₂O₃
  • Molecular Weight 242.22
  • Synonym(s) Roflumilast intermediates-2
  • SMILES O=CC1=CC=C(OC(F)F)C(OCC2CC2)=C1

Synthesis

  • Route1
    • In-stock
      Cyclopropylmethyl bromide|CS-W020194
      7051-34-5
    • 4-Difluoromethoxy-3-hydroxybenzaldehyde Roflumilast  Impurity|CS-0229135
      151103-08-1
    • ~96%
    • In-stock
      3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde|CS-W006995
      151103-09-2

    References

    • INTERQUIM, S.A.; SALAET FERRE, Josep; MARQUILLAS OLONDRIZ, Francisco Patent: WO2014/60464 A1, 2014 ; Location in patent: Page/Page column 15 ;
  • Route2

    References

    • Armani, Elisabetta; Amari, Gabriele; Rizzi, Andrea; Fanti, Renato De; Ghidini, Eleonora; Capaldi, Carmelida; Carzaniga, Laura; Caruso, Paola; Guala, Matilde; Peretto, Ilaria; La Porta, Elena; Bolzoni, Pier T.; Facchinetti, Fabrizio; Carnini, Chiara; Moretto, Nadia; Patacchini, Riccardo; Bassani, Franco; Cenacchi, Valentina; Volta, Roberta; Amadei, Francesco; Capacchi, Silvia; Delcanale, Maurizio; Puccini, Paola; Catinella, Silvia; Civelli, Maurizio; Villetti, Gino Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 793 - 816

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   2.8893
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   6

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