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CS-W001157 4
Total: USD 88.00

Cyclopropyl 3-methylphenyl ketone

  • CAS No. 150668-37-4

  • Cat. No. CS-0153231
  • Purity≥97%
  • MDL No.MFCD03841207

*For research and further manufacturing use only, not for direct human use.

Cyclopropyl 3-methylphenyl ketone|CS-0153231

Structure of 150668-37-4

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General Information

  • CAS No. 150668-37-4
  • Cat. No. CS-0153231
  • Purity ≥97%
  • MDL No. MFCD03841207
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂O
  • Molecular Weight 160.21
  • Synonym(s) cyclopropyl(m-tolyl)methanone
  • SMILES CC1=CC(=CC=C1)C(=O)C2CC2

Description

Cyclopropyl 3-methylphenyl ketone features a cyclopropyl group attached to a ketone-bearing aromatic ring with a meta-methyl substituent. This structural motif delivers enhanced steric rigidity and lipophilicity, enabling its use in medicinal chemistry scaffolds and as a building block for bioactive molecules requiring defined spatial orientation and membrane permeability.

Application

Cyclopropyl 3-methylphenyl ketone serves as a versatile building block in medicinal chemistry, enabling the construction of biologically active scaffolds through standard carbonyl transformations. Its structure combines a cyclopropyl group with an ortho-methyl-substituted phenyl ring, offering enhanced metabolic stability and defined steric profiles. The ketone functionality facilitates nucleophilic additions, reductive aminations, and Grignard reactions under mild conditions, supporting efficient synthesis of complex intermediates. Bench-stable and readily purified by chromatography or crystallization, it functions reliably in multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.58772
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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