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CS-W001157 4
Total: USD 88.00

2-Methoxycinnamaldehyde

  • CAS No. 1504-74-1

  • Cat. No. CS-0065992
  • Purity≥98%
  • MDL No.MFCD00007001

*For research and further manufacturing use only, not for direct human use.

2-Methoxycinnamaldehyde|CS-0065992

Structure of 1504-74-1

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General Information

  • CAS No. 1504-74-1
  • Cat. No. CS-0065992
  • Purity ≥98%
  • MDL No. MFCD00007001
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₂
  • Molecular Weight None
  • Synonym(s) o-Methoxycinnamaldehyde
  • SMILES O=C/C=C/C1=CC=CC=C1OC

Description

2-Methoxycinnamaldehyde is one of the components of Cinnamomum cassia. It was identified using high-pressure liquid chromatography (HPLC) and gas chromatographymass spectrometry.

Application

2-Methoxycinnamaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted chalcones and heterocyclic scaffolds via [4+2] cycloadditions and aldol-type condensations. Its conjugated aldehyde and methoxy functionalities provide predictable reactivity, excellent bench stability, and compatibility with a range of functional groups, facilitating straightforward purification and scalability in medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1
    • null|null
      1504-61-6
    • ~95%
    • In-stock
      2-Methoxycinnamaldehyde|CS-0065992
      1504-74-1

    References

    • Jiang, Jian-An; Du, Jia-Lei; Wang, Zhan-Guo; Zhang, Zhong-Nan; Xu, Xi; Zheng, Gan-Lin; Ji, Ya-Fei Tetrahedron Letters, 2014 , vol. 55, # 10 p. 1677 - 1681
  • Route2
    • null|null
      33538-83-9
    • ~46%
    • In-stock
      2-Methoxycinnamaldehyde|CS-0065992
      1504-74-1

    References

    • Liu, Jie; Zhu, Jin; Jiang, Hualiang; Wang, Wei; Li, Jian Chemistry - An Asian Journal, 2009 , vol. 4, # 11 p. 1712 - 1716
  • Route3
    • 1-Allyl-2-methoxybenzene|CS-0267269
      3698-28-0
    • ~88%
    • In-stock
      2-Methoxycinnamaldehyde|CS-0065992
      1504-74-1

    References

    • Chang, Meng-Yang; Lin, Shin-Ying; Chan, Chieh-Kai Synlett, 2013 , vol. 24, # 4 art. no. ST-2012-W1070-L, p. 487 - 490

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.9073
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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