2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid

Name: 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1503461-20-8
Cat. No. CS-0055227
Purity≥98%
MDL No.MFCD20259410

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid|CS-0055227

Structure of 1503461-20-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1503461-20-8
Cat. No. CS-0055227
Purity ≥98%
MDL No. MFCD20259410
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄ClN₃O₂
Molecular Weight 197.58
Synonym(s) None
SMILES O=C(C1=CC2=CN=C(Cl)N=C2N1)O

Description

2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid features a fused heterocyclic core with orthogonal functional handles: a chloro group at C2 and a carboxylic acid at C6. This arrangement enables direct incorporation into bioactive scaffolds via amide coupling or nucleophilic substitution. The electron-deficient pyrimidine ring enhances reactivity in cross-coupling processes, while the bench-stable carboxylate supports modular derivatization under standard conditions.

Application

2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid serves as a versatile building block for purine-derived scaffolds in medicinal chemistry. Its carboxylic acid functionality enables direct amidation or esterification, while the chloro substituent facilitates palladium-catalyzed coupling reactions. The molecule exhibits good bench stability and functional group tolerance, supporting efficient synthesis of heterocyclic intermediates relevant to kinase inhibitors and nucleoside analogs.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 78.87
LogP 1.3095
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

1503461-20-8 sigma1503461-20-8 manufacturer1503461-20-8 price1503461-20-8 structure1503461-20-8 SDSbuy 1503461-20-81503461-20-8 supplier1503461-20-8 uses1503461-20-8 molecular weightprice of 1503461-20-81503461-20-8 chemical name formula of 1503461-20-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid

CAS No. 1503461-20-8

Recommended Products