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CS-W001157 4
Total: USD 88.00

2-Bromobenzo[d]thiazole-6-carboxamide

  • CAS No. 1502927-80-1

  • Cat. No. CS-0198943
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Bromobenzo[d]thiazole-6-carboxamide|CS-0198943

Structure of 1502927-80-1

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General Information

  • CAS No. 1502927-80-1
  • Cat. No. CS-0198943
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂OS
  • Molecular Weight 257.11
  • Synonym(s) None
  • SMILES NC(C1=CC=2SC(Br)=NC2C=C1)=O

Description

2-Bromobenzo[d]thiazole-6-carboxamide features a brominated benzothiazole core paired with a carboxamide group, enabling direct integration into bioactive scaffolds. This configuration supports efficient coupling reactions and provides enhanced metabolic stability in pharmaceutical applications.

Application

2-Bromobenzo[d]thiazole-6-carboxamide serves as a versatile building block in medicinal chemistry, enabling efficient access to biologically active heterocycles. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the carboxamide group offers hydrogen-bonding capacity and metabolic stability. The scaffold demonstrates excellent bench stability and compatibility with standard synthetic protocols, supporting rapid diversification in lead optimization campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   55.98
  • LogP   2.1577
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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