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CS-W001157 4
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(4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Minocycline Impurity

  • CAS No. 149934-19-0

  • Cat. No. CS-0164641
  • Purity≥98%
  • MDL No.MFCD14666524

*For research and further manufacturing use only, not for direct human use.

(4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Minocycline Impurity|CS-0164641

Structure of 149934-19-0

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General Information

  • CAS No. 149934-19-0
  • Cat. No. CS-0164641
  • Purity ≥98%
  • MDL No. MFCD14666524
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₈N₄O₇
  • Molecular Weight 472.49
  • Synonym(s) None
  • SMILES O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(N)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N

Synthesis

  • Route1
    • null|null
      149934-17-8
    • ~%
    • (4S,4aS,5aR,12aS)-9-Amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Minocycline Impurity|CS-0164641
      149934-19-0

    References

    • WYETH LLC; YANG, ChunHua; DILLON, John Leo Jr.; NAIK, Ramachandra Patent: WO2010/114680 A1, 2010 ; Location in patent: Page/Page column 27-28 ;
  • Route2

    References

    • Sum, Phaik-Eng; Ross, Adma T.; Petersen, Peter J.; Testa, Raymond T. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 2 p. 400 - 403

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H361-H373
Precautionary Statements : P260-P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   190.65
  • LogP   -0.2312
  • H_Acceptors   10
  • H_Donors   6
  • Rotatable_Bonds   3

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