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CS-W001157 4
Total: USD 88.00

4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid

  • CAS No. 149353-75-3

  • Cat. No. CS-W021981
  • Purity≥98%
  • MDL No.MFCD02178897

*For research and further manufacturing use only, not for direct human use.

4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid|CS-W021981

Structure of 149353-75-3

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General Information

  • CAS No. 149353-75-3
  • Cat. No. CS-W021981
  • Purity ≥98%
  • MDL No. MFCD02178897
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₃NO₄
  • Molecular Weight 305.37
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=C(C=C1)C2CCN(C(=O)OC(C)(C)C)CC2

Description

This piperidine-based benzoic acid derivative features a tert-butoxycarbonyl-protected amine, enabling stable incorporation into peptide and small-molecule conjugates. The electron-rich aromatic core enhances solubility and facilitates downstream functionalization under standard conditions.

Application

4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and peptide conjugates. The tert-butyl carbamate group provides stable protection of the piperidine nitrogen, enabling selective deprotection under mild acidic conditions. The benzoic acid moiety facilitates coupling reactions via amide or ester formation, supporting applications in medicinal chemistry and fragment-based drug discovery.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H315-H317-H319-H410
Precautionary Statements : P261-P264-P272-P273-P280-P302+P352-P362-P391-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   3.4993
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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