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CS-W001157 4
Total: USD 88.00

6-Chloro-N-methoxy-N-methylnicotinamide

  • CAS No. 149281-42-5

  • Cat. No. CS-0172389
  • Purity≥98%
  • MDL No.MFCD09991647

*For research and further manufacturing use only, not for direct human use.

6-Chloro-N-methoxy-N-methylnicotinamide|CS-0172389

Structure of 149281-42-5

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General Information

  • CAS No. 149281-42-5
  • Cat. No. CS-0172389
  • Purity ≥98%
  • MDL No. MFCD09991647
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉ClN₂O₂
  • Molecular Weight 200.62
  • Synonym(s) 6-Chloro-N-methoxy-N-methylpyridine-3-carboxamide, 2-Chloro-5-[methoxy(methyl)carbamoyl]pyridine
  • SMILES CN(C(=O)C1=CN=C(C=C1)Cl)OC

Synthesis

  • Route1

    References

    • Dehmlow, Henrietta; Aebi, Johannes D.; Jolidon, Synese; Ji, Yu-Hua; Von der Mark, Elisabeth M.; Himber, Jacques; Morand, Olivier H. Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3354 - 3370
  • Route2

    References

    • PFIZER PRODUCTS INC.? Patent: WO2005/60967 A1, 2005 ; Location in patent: Page/Page column 21 ; WO 2005/060967 A1
  • Route3
    • In-stock
      6-Chloronicotinoyl chloride|CS-W017428
      58757-38-3
    • null|null
      1117-97-1
    • ~89%
    • In-stock
      6-Chloro-N-methoxy-N-methylnicotinamide|CS-0172389
      149281-42-5

    References

    • ABBOTT GMBH and; CO. KG; TURNER, Sean Colm; BAKKER, Margaretha Henrica Maria; HORNBERGER, Wilfried; WOLTER, Falko Ernst Patent: WO2010/109005 A1, 2010 ; Location in patent: Page/Page column 54 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   42.43
  • LogP   1.3684
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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