N-Methyl-[1,1'-biphenyl]-2-amine

Name: N-Methyl-[1,1'-biphenyl]-2-amine
Brand: ChemScene
Availability: InStock
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CAS No. 14925-09-8
Cat. No. CS-W019420
Purity≥96%
MDL No.MFCD00179576

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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N-Methyl-[1,1'-biphenyl]-2-amine|CS-W019420

Structure of 14925-09-8

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Description

N-Methyl-[1,1'-biphenyl]-2-amine features a sterically accessible aniline nitrogen bearing a methyl substituent, enhancing electron density at the ortho position. This configuration supports efficient coupling in transition-metal-catalyzed reactions and provides improved solubility in organic media compared to unsubstituted analogs. The biphenyl scaffold imparts stability and facilitates π-stacking interactions in coordination environments.

Application

N-Methyl-[1,1'-biphenyl]-2-amine serves as a versatile building block in medicinal chemistry and catalytic synthesis, offering enhanced solubility and metabolic stability over parent aniline derivatives. Its ortho-methylated biphenyl core enables efficient transition-metal-catalyzed coupling reactions, while the N-methyl group provides steric and electronic modulation. The compound exhibits good bench stability, facilitates purification via standard chromatographic methods, and functions effectively in the construction of biologically active heterocyclic scaffolds and functionalized arylamines.

General Information

CAS No. 14925-09-8
Cat. No. CS-W019420
Purity ≥96%
MDL No. MFCD00179576
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₃N
Molecular Weight 183.25
Synonym(s) o-(N-Methylamino)biphenyl
SMILES CNC1=C(C2=CC=CC=C2)C=CC=C1

Computational Chemistry Data

TPSA 12.03
LogP 3.3953
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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N-Methyl-[1,1'-biphenyl]-2-amine

CAS No. 14925-09-8

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