Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Cyano-1-pentyne

  • CAS No. 14918-21-9

  • Cat. No. CS-0196806
  • Purity≥96%
  • MDL No.MFCD00001978

*For research and further manufacturing use only, not for direct human use.

5-Cyano-1-pentyne|CS-0196806

Structure of 14918-21-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 14918-21-9
  • Cat. No. CS-0196806
  • Purity ≥96%
  • MDL No. MFCD00001978
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇N
  • Molecular Weight 93.13
  • Synonym(s) None
  • SMILES N#CCCCC#C

Description

Mal-PEG2-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Application

5-Cyano-1-pentyne serves as a versatile building block in synthetic organic chemistry, enabling efficient access to nitrile-containing alkynes for subsequent transformations. Its terminal alkyne functionality facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the pendant nitrile group offers compatibility with nucleophilic additions and functionalization under mild conditions. The molecule exhibits excellent bench stability and is readily purified by distillation or column chromatography, making it well-suited for use in multistep syntheses of complex heterocycles and pharmaceutical intermediates.

Synthesis

  • Route1
    • null|null
      14267-92-6
    • ~54%
    • In-stock
      5-Cyano-1-pentyne|CS-0196806
      14918-21-9

    References

    • Katz; Shih; Ying; Stuart Journal of the American Chemical Society, 1984 , vol. 106, # 9 p. 2659 - 2668
  • Route2
    • Pent-4-yn-1-yl 4-methylbenzenesulfonate|CS-0109787
      77758-50-0
    • ~%
    • In-stock
      5-Cyano-1-pentyne|CS-0196806
      14918-21-9

    References

    • Helvetica Chimica Acta, , vol. 63, # 8 p. 2312 - 2319
  • Route3

    References

    • Helvetica Chimica Acta, , vol. 63, # 8 p. 2312 - 2319

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302+H312+H332-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P370+P378-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   23.79
  • LogP   1.31348
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Cyano-1-pentyne sigma5-Cyano-1-pentyne manufacturer5-Cyano-1-pentyne price5-Cyano-1-pentyne structure5-Cyano-1-pentyne SDSbuy 5-Cyano-1-pentyne5-Cyano-1-pentyne supplier5-Cyano-1-pentyne uses5-Cyano-1-pentyne molecular weightprice of 5-Cyano-1-pentyne5-Cyano-1-pentyne chemical name formula of 5-Cyano-1-pentyne
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label