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CS-W001157 4
Total: USD 88.00

6-Nitropyridin-3-amine

  • CAS No. 14916-65-5

  • Cat. No. CS-W018717
  • Purity≥96%
  • MDL No.MFCD01646117

*For research and further manufacturing use only, not for direct human use.

6-Nitropyridin-3-amine|CS-W018717

Structure of 14916-65-5

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General Information

  • CAS No. 14916-65-5
  • Cat. No. CS-W018717
  • Purity ≥96%
  • MDL No. MFCD01646117
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅N₃O₂
  • Molecular Weight 139.11
  • Synonym(s) 6-Nitro-pyridin-3-ylamine
  • SMILES NC1=CN=C(C=C1)[N+](=O)[O-]

Description

6-Nitropyridin-3-amine features a pyridine core bearing both nitro and primary amine groups at meta positions, enabling dual reactivity. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds and serves as a key intermediate in the synthesis of kinase inhibitors and functionalized pharmaceuticals.

Application

6-Nitropyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via standard coupling reactions. Its dual functionality—nitro group for reduction or substitution and primary amine for derivatization—supports diverse downstream transformations. Bench-stable and readily purified, it facilitates efficient synthesis of pyridine-based API candidates and functionalized intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   82.05
  • LogP   0.572
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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