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CS-W001157 4
Total: USD 88.00

(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde

  • CAS No. 148901-68-2

  • Cat. No. CS-0186100
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde|CS-0186100

Structure of 148901-68-2

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General Information

  • CAS No. 148901-68-2
  • Cat. No. CS-0186100
  • Purity ≥95%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₆FNO
  • Molecular Weight 317.36
  • Synonym(s) (E)-3'-[4-(4'-FLUOROPHENYL)-2-(CYCLOPROPYL)-3-QUINOLINYL]-2-PROPENAL
  • SMILES C1=CC=C2C(=C1)C(=C(/C=C/C=O)C(=N2)C3CC3)C4=CC=C(C=C4)F

Synthesis

  • Route1
    • (E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylonitrile|CS-0156041
      256431-72-8
    • ~88%
    • (E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde|CS-0186100
      148901-68-2

    References

    • Suzuki; Iwasaki; Fujikawa; Kitahara; Sakashita; Sakoda Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 10 p. 2727 - 2743
  • Route2
    • null|null
      113832-57-8
    • In-stock
      2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde|CS-0156035
      121660-37-5
    • ~81%
    • (E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde|CS-0186100
      148901-68-2

    References

    • Nissan Chemical Industries, Ltd. Patent: EP1614682 A1, 2006 ; Location in patent: Page/Page column 6 ;
  • Route3

    References

    • Nissan Chemical Industries, Ltd. Patent: EP1614682 A1, 2006 ; Location in patent: Page/Page column 6 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   5.1304
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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