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CS-W001157 4
Total: USD 88.00

4-Methoxy-1H-pyrazole

  • CAS No. 14884-01-6

  • Cat. No. CS-0050823
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Methoxy-1H-pyrazole|CS-0050823

Structure of 14884-01-6

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General Information

  • CAS No. 14884-01-6
  • Cat. No. CS-0050823
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₂O
  • Molecular Weight 98.10
  • Synonym(s) None
  • SMILES COC1=CNN=C1

Description

4-Methoxy-1H-pyrazole is a bench-stable heterocyclic compound featuring a pyrazole core with a methoxy group at the 4-position. This substitution enhances solubility in polar solvents and imparts favorable electronic properties for use in medicinal chemistry and catalyst design. The molecule integrates readily into complex scaffolds through its reactive nitrogen sites.

Application

4-Methoxy-1H-pyrazole serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic applications. Its electron-donating methoxy group enhances nucleophilicity at C3, enabling reliable functionalization in cross-coupling and electrophilic substitution reactions. The compound exhibits good bench stability, facilitates purification by standard chromatography, and functions as a key scaffold in the synthesis of bioactive molecules and agrochemical intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.91
  • LogP   0.4183
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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