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Structure of 148438-03-3
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Methyl 4-cyclopropylbenzoate features a cyclopropyl group positioned para to the ester functionality, imparting enhanced lipophilicity and metabolic stability. This structural motif enables efficient integration into bioactive scaffolds and synthetic intermediates requiring rigid, electron-rich aromatic systems under standard conditions.
Methyl 4-cyclopropylbenzoate serves as a versatile synthetic intermediate for the construction of biologically relevant arylcarboxylates and heterocyclic scaffolds. Its cyclopropyl substituent imparts enhanced metabolic stability and modulates lipophilicity, making it valuable in medicinal chemistry campaigns. The ester functionality enables straightforward derivatization via hydrolysis, reduction, or coupling reactions, while the aromatic core supports electrophilic substitution and transition-metal-catalyzed transformations. Bench-stable and readily purified by recrystallization or column chromatography, it functions as a reliable building block in multi-step synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: