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CS-W001157 4
Total: USD 88.00

3,4-Dihydro-2H-1-benzopyran-4-ol

  • CAS No. 1481-93-2

  • Cat. No. CS-0074553
  • Purity≥98%
  • MDL No.MFCD00006849

*For research and further manufacturing use only, not for direct human use.

3,4-Dihydro-2H-1-benzopyran-4-ol|CS-0074553

Structure of 1481-93-2

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General Information

  • CAS No. 1481-93-2
  • Cat. No. CS-0074553
  • Purity ≥98%
  • MDL No. MFCD00006849
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₂
  • Molecular Weight 150.17
  • Synonym(s) 4-Hydroxychroman
  • SMILES OC1C(C=CC=C2)=C2OCC1

Description

4-Chromanol was used in preparation of 4--L-rhamnopyranosyloxychromanol, glycosyl flavonoid, by glycosylation.

Application

3,4-Dihydro-2H-1-benzopyran-4-ol serves as a versatile scaffold in synthetic organic chemistry, enabling the construction of bioactive heterocycles and natural product analogs. Its phenolic hydroxyl group facilitates selective derivatization, while the dihydropyran core offers stability and compatibility with standard coupling and oxidation protocols. This compound functions as a key intermediate in the synthesis of flavonoid derivatives and other pharmacologically relevant architectures.

Synthesis

  • Route1

    References

    • Dieskau, Andre P.; Begouin, Jeanne-Marie; Plietker, Bernd European Journal of Organic Chemistry, 2011 , # 27 p. 5291 - 5296
  • Route2
    • null|null
      92971-91-0
    • ~%
    • In-stock
      3,4-Dihydro-2H-1-benzopyran-4-ol|CS-0074553
      1481-93-2
    • null|null
      22409-86-5

    References

    • Tetrahedron Letters, , vol. 53, # 33 p. 4280 - 4282
  • Route3

    References

    • Semeniuchenko, Volodymyr; Exner, Thomas E.; Khilya, Volodymyr; Groth, Ulrich Applied Organometallic Chemistry, 2011 , vol. 25, # 11 p. 804 - 809

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   1.5025
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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