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CS-W001157 4
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2,3-Dihydroxyterephthalaldehyde

  • CAS No. 148063-59-6

  • Cat. No. CS-0110551
  • Molecule weight166.13
  • Purity≥97%
  • MDL No.MFCD24394548

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydroxyterephthalaldehyde|CS-0110551

Structure of 148063-59-6

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General Information

  • CAS No. 148063-59-6
  • Cat. No. CS-0110551
  • Purity ≥97%
  • MDL No. MFCD24394548
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆O₄
  • Molecular Weight 166.13
  • Synonym(s) 1,4-Benzenedicarboxaldehyde, 2,3-dihydroxy-
  • SMILES O=CC1=CC=C(C(O)=C1O)C=O

Description

2,3-Dihydroxyterephthalaldehyde features two hydroxyl groups adjacent to a terephthalic aldehyde core, enabling versatile coordination in metal complexation and efficient integration into chelating ligands. The ortho-diol moiety enhances solubility and stability under physiological conditions, while the aldehyde functionality facilitates nucleophilic addition reactions. This structure supports applications in supramolecular chemistry and sensor development.

Application

2,3-Dihydroxyterephthalaldehyde serves as a versatile building block in synthetic organic chemistry, enabling the construction of complex heterocyclic scaffolds and bioactive molecule cores. Its ortho-dihydroxy and dialdehyde functionalities offer high reactivity in condensation reactions, facilitating the formation of oxazines, quinones, and polyaromatic systems under mild conditions. The compound exhibits good bench stability and is readily purified by crystallization, making it suitable for iterative synthesis workflows in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   0.7228
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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