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CS-W001157 4
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5-Phenylthiophen-2-amine

  • CAS No. 14770-85-5

  • Cat. No. CS-0156418
  • Purity≥95%
  • MDL No.MFCD11904083

*For research and further manufacturing use only, not for direct human use.

5-Phenylthiophen-2-amine|CS-0156418

Structure of 14770-85-5

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General Information

  • CAS No. 14770-85-5
  • Cat. No. CS-0156418
  • Purity ≥95%
  • MDL No. MFCD11904083
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NS
  • Molecular Weight 175.25
  • Synonym(s) 5-Phenyl-thiophen-2-ylamine
  • SMILES C1=CC=C(C=C1)C2=CC=C(N)S2

Description

5-Phenylthiophen-2-amine features a thiophene core fused to a phenyl ring and an amino group at the 2-position, delivering enhanced electron density for use in conjugated materials. This scaffold enables direct integration into organic semiconductors and functional dyes, offering improved charge transport properties and stability under ambient conditions.

Application

5-Phenylthiophen-2-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of functionalized thiophene-based scaffolds. Its phenylthio substituent enhances electronic modulation and provides orthogonal reactivity for downstream derivatization. The amine group facilitates coupling reactions and salt formation, while the molecule exhibits good bench stability and ease of purification—key attributes for scalable synthesis and process development.

Synthesis

  • Route1
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      883745-73-1
    • ~81%
    • In-stock
      5-Phenylthiophen-2-amine|CS-0156418
      14770-85-5

    References

    • NPS PHARMACEUTICALS, INC.; GLAXOSMITHKLINE Patent: WO2006/41968 A1, 2006 ; Location in patent: Page/Page column 43 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.9973
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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