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CS-W001157 4
Total: USD 88.00

Tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Pitavastatin Impurity

  • CAS No. 147489-06-3

  • Cat. No. CS-0167164
  • Molecule weight517.63
  • Purity≥98%
  • MDL No.MFCD12911897

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Pitavastatin Impurity|CS-0167164

Structure of 147489-06-3

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General Information

  • CAS No. 147489-06-3
  • Cat. No. CS-0167164
  • Purity ≥98%
  • MDL No. MFCD12911897
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₂H₃₆FNO₄
  • Molecular Weight 517.63
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)C[C@@H]1OC(C)(C)O[C@H](/C=C/C2=C(C3=CC=C(F)C=C3)C4=CC=CC=C4N=C2C5CC5)C1

Synthesis

  • Route1
    • null|null
      1234331-54-4
    • tert-Butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate Rosuvastatin Impurity|CS-0167482
      124752-23-4
    • ~84%
    • Tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Pitavastatin Impurity|CS-0167164
      147489-06-3

    References

    • WO2010/77062 A2, ; Page/Page column 13-14 ;
  • Route2
    • null|null
      153968-97-9
    • null|null
      153968-91-3
    • ~78%
    • Tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Pitavastatin Impurity|CS-0167164
      147489-06-3

    References

    • Bulletin of the Chemical Society of Japan, , vol. 68, # 9 p. 2649 - 2656
  • Route3
    • null|null
      5292-43-3
    • ~%
    • Tert-butyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Pitavastatin Impurity|CS-0167164
      147489-06-3

    References

    • Bulletin of the Chemical Society of Japan, , vol. 68, # 9 p. 2649 - 2656

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.65
  • LogP   7.5735
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   6

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