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CS-W001157 4
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Methyl 2-ethoxy-1-[[2′-(hydroxyamidino)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate

  • CAS No. 147403-65-4

  • Cat. No. CS-0008002
  • Molecule weight444.49
  • Purity≥98%
  • MDL No.MFCD21496678

*For research and further manufacturing use only, not for direct human use.

Methyl 2-ethoxy-1-[[2′-(hydroxyamidino)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate|CS-0008002

Structure of 147403-65-4

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General Information

  • CAS No. 147403-65-4
  • Cat. No. CS-0008002
  • Purity ≥98%
  • MDL No. MFCD21496678
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₄N₄O₄
  • Molecular Weight 444.49
  • Synonym(s) Methyl 2-ethoxy-1-((2'-(N-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
  • SMILES O=C(OC)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C(=N)NO

Synthesis

  • Route1

    References

    • RANBAXY LABORATORIES LIMITED; AZAD, Md Abul Kalam; KSHIRSAGAR, Prakash Bhimaji; SINGH, Shravan, Kumar; TIWARI, Anand, Prakash; SINGH, Kaptan; PRASAD, Mohan; ARORA, Sudershan, Kumar Patent: WO2013/114305 A1, 2013 ; Location in patent: Page/Page column 15; 16 ;
  • Route2
    • null|null
      1403477-45-1
    • ~7%
    • In-stock
      Methyl 2-ethoxy-1-[[2′-(hydroxyamidino)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate|CS-0008002
      147403-65-4
    • In-stock
      Azilsartan|CS-1396
      147403-03-0

    References

    • WO2012/139535 A1, ; Page/Page column 12-13 ;
  • Route3
    • In-stock
      Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate|CS-0151435
      139481-44-0
    • ~%
    • Azilsartan impurity 25|CS-0720539
      139481-33-7
    • In-stock
      Methyl 2-ethoxy-1-[[2′-(hydroxyamidino)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate|CS-0008002
      147403-65-4

    References

    • WO2012/119573 A1, ; Page/Page column 12-13 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   97.97
  • LogP   4.2496
  • H_Acceptors   8
  • H_Donors   2
  • Rotatable_Bonds   8

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