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Structure of 147285-87-8
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4-Fluoro-2-methyl-6-nitroaniline features a trifunctional aromatic core with electron-withdrawing nitro and fluorine groups paired with an activating methyl substituent. This combination enables selective coupling reactions under mild conditions, making it valuable for synthesizing functionalized heterocycles and pharmaceutical intermediates in biopharmaceutical development workflows.
4-Fluoro-2-methyl-6-nitroaniline serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via nucleophilic aromatic substitution or subsequent reduction of the nitro group. The fluorine and methyl substituents provide orthogonal reactivity and steric modulation, while the nitro group facilitates downstream functionalization. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step syntheses requiring precise regiocontrol.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: