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CS-W001157 4
Total: USD 88.00

(S)-1-Boc-3-aminopyrrolidine

  • CAS No. 147081-44-5

  • Cat. No. CS-D0665
  • Purity≥98%
  • MDL No.MFCD03419271

*For research and further manufacturing use only, not for direct human use.

(S)-1-Boc-3-aminopyrrolidine|CS-D0665

Structure of 147081-44-5

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General Information

  • CAS No. 147081-44-5
  • Cat. No. CS-D0665
  • Purity ≥98%
  • MDL No. MFCD03419271
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈N₂O₂
  • Molecular Weight 186.25
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N(CC1)C[C@H]1N

Description

(S)-(-)-1-Boc-3-aminopyrrolidine may be used to prepare:Descarboxamide analog of 4-N-(N-nitro-L-argininyl)-trans-4-amino-L-proline amide.Histamine 3 (H3) receptor antagonists containing pyrrolidin-3-yl-N-methylbenzamide moiety.

Synthesis

  • Route1
    • null|null
      125552-56-9
    • ~95%
    • In-stock
      (S)-1-Boc-3-aminopyrrolidine|CS-D0665
      147081-44-5

    References

    • Vetoquinol SA Patent: US2009/221565 A1, 2009 ; Location in patent: Page/Page column 51 ; US 20090221565 A1
  • Route2

    References

    • Wagner, Eva; Wittmann, Hans-Joachim; Elz, Sigurd; Strasser, Andrea Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 21 p. 6274 - 6280
  • Route3

    References

    • EP1460061 A1, ; Page 5-6 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H227-H301-H318-H411
Precautionary Statements : P210-P264-P270-P273-P280-P330-P370+P378-P391-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   0.9545
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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