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CS-W001157 4
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3-(Methylamino)phenol

  • CAS No. 14703-69-6

  • Cat. No. CS-0151034
  • Purity≥97%
  • MDL No.MFCD16998628

*For research and further manufacturing use only, not for direct human use.

3-(Methylamino)phenol|CS-0151034

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General Information

  • CAS No. 14703-69-6
  • Cat. No. CS-0151034
  • Purity ≥97%
  • MDL No. MFCD16998628
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO
  • Molecular Weight 123.15
  • Synonym(s) N-Methyl-m-hydroxyaniline
  • SMILES CNC1=CC(=CC=C1)O

Description

3-(Methylamino)phenol features a phenolic hydroxyl group and a methylamino substituent positioned ortho to each other, creating a uniquely reactive scaffold. This arrangement enables direct incorporation into bioactive molecule synthesis, particularly in pharmaceutical intermediates requiring enhanced solubility and metabolic stability. The compound exhibits favorable handling characteristics under standard bench conditions.

Application

3-(Methylamino)phenol serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-diamine-like reactivity facilitates efficient cyclization with carbonyl compounds and electrophiles, while the methylamino group offers tunable basicity and metabolic stability. The compound exhibits good bench stability and is compatible with standard purification protocols, making it suitable for scalable synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   1.4339
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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