Lot numbers can be found on the outside label of a product:
Isoxazol-5-amine
-
CAS No. 14678-05-8
- Cat. No. CS-W005361
- Purity≥98%
- MDL No.MFCD00128192
*For research and further manufacturing use only, not for direct human use.
Structure of 14678-05-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 14678-05-8
- Cat. No. CS-W005361
- Purity ≥98%
- MDL No. MFCD00128192
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₃H₄N₂O
- Molecular Weight 84.08
- Synonym(s) Isoxazol-5-ylamine
- SMILES NC1=CC=NO1
Description
Isoxazol-5-amine is a nitrogen-rich heterocycle featuring a reactive amine group at the 5-position, enabling direct functionalization in synthetic transformations. This bench-stable scaffold integrates readily into bioactive molecules and serves as a key building block for pharmaceutical intermediates and agrochemicals.
Application
Isoxazol-5-amine serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its primary amine functionality enables straightforward derivatization via acylation, alkylation, and coupling reactions. The isoxazole core exhibits good bench stability and compatibility with common protecting group strategies, facilitating its use in multi-step syntheses. This scaffold functions as a key motif in bioactive molecule design, particularly for compounds requiring polar, hydrogen-bonding capabilities within the pharmacophore.
Synthesis
-
Route1
-
1070-71-9 - ~29%
-
In-stock
14678-05-8
References
-
Takeda Pharmaceutical Company Limited Patent: EP1813606 A1, 2007 ; Location in patent: Page/Page column 89 ;
-
-
Route2
-
60838-50-8
-
In-stock
7803-49-8 - ~%
-
In-stock
14678-05-8
References
-
WO2006/90143 A1, ; Page/Page column 51-52 ; WO 2006/090143 A1
-
-
Route3
-
In-stock
7341-96-0 - ~%
-
In-stock
14678-05-8
References
-
Chemical and Pharmaceutical Bulletin, , vol. 14, # 11 p. 1277 - 1286
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 52.05
- LogP 0.2568
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Isoxazol-5-amine sigmaIsoxazol-5-amine manufacturerIsoxazol-5-amine priceIsoxazol-5-amine structureIsoxazol-5-amine SDSbuy Isoxazol-5-amineIsoxazol-5-amine supplierIsoxazol-5-amine usesIsoxazol-5-amine molecular weightprice of Isoxazol-5-amineIsoxazol-5-amine chemical name formula of Isoxazol-5-amine