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3-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoic acid

  • CAS No. 14676-03-0

  • Cat. No. CS-0133012
  • Molecule weight255.27
  • Purity≥95%
  • MDL No.MFCD02090673

*For research and further manufacturing use only, not for direct human use.

3-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoic acid|CS-0133012

Structure of 14676-03-0

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General Information

  • CAS No. 14676-03-0
  • Cat. No. CS-0133012
  • Purity ≥95%
  • MDL No. MFCD02090673
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇NO₅
  • Molecular Weight 255.27
  • Synonym(s) N-Boc-RS-3-Amino-3-(2-furyl)propionic acid
  • SMILES O=C(O)CC(NC(OC(C)(C)C)=O)C1=CC=CO1

Description

This protected amino acid derivative features a furan-2-yl group flanked by a tert-butoxycarbonyl (Boc) amine and a carboxylic acid, enabling direct incorporation into peptide chains. The Boc moiety ensures stability during synthesis, while the electron-rich furan ring enhances reactivity in coupling reactions under standard conditions.

Application

3-((tert-Butoxycarbonyl)amino)-3-(furan-2-yl)propanoic acid serves as a versatile building block for the synthesis of furan-containing amino acid derivatives. The tert-butoxycarbonyl (Boc) group provides excellent stability and orthogonal deprotection compatibility, while the pendant furan moiety enables facile incorporation into heterocyclic scaffolds. Its well-defined reactivity facilitates straightforward peptide coupling and functionalization under standard conditions, offering reliable access to biologically relevant motifs in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   88.77
  • LogP   2.3201
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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