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CS-W001157 4
Total: USD 88.00

8-(phenylmethyl)-2,8-Diazaspiro[4.5]decane-1,3-dione

  • CAS No. 1463-48-5

  • Cat. No. CS-0000537
  • Purity98+%
  • MDL No.MFCD11043250

*For research and further manufacturing use only, not for direct human use.

8-(phenylmethyl)-2,8-Diazaspiro[4.5]decane-1,3-dione|CS-0000537

Structure of 1463-48-5

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General Information

  • CAS No. 1463-48-5
  • Cat. No. CS-0000537
  • Purity 98+%
  • MDL No. MFCD11043250
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₈N₂O₂
  • Molecular Weight 258.32
  • Synonym(s) 8-Benzyl-2,8-diazaspiro[4.5]decane-1,3-dione
  • SMILES O=C(C12CCN(CC3=CC=CC=C3)CC1)NC(C2)=O

Synthesis

  • Route1
    • 1-Benzyl-4-(cyanomethyl)piperidine-4-carbonitrile|CS-M1533
      86945-27-9
    • ~79%
    • 8-(phenylmethyl)-2,8-Diazaspiro[4.5]decane-1,3-dione|CS-0000537
      1463-48-5

    References

    • NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2004/76455 A1, 2004 ; Location in patent: Page 18; 34 ; WO 2004/076455 A1
  • Route2
    • null|null
      3612-20-2
    • null|null
      105-56-6
    • ~%
    • 8-(phenylmethyl)-2,8-Diazaspiro[4.5]decane-1,3-dione|CS-0000537
      1463-48-5

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 14 p. 1851 - 1856

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.41
  • LogP   1.3153
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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