1H-Pyrrolo[2,3-b]pyridin-6-amine

Name: 1H-Pyrrolo[2,3-b]pyridin-6-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 145901-11-7
Cat. No. CS-W019627
Purity≥96%
MDL No.MFCD08272224

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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1H-Pyrrolo[2,3-b]pyridin-6-amine|CS-W019627

Structure of 145901-11-7

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Description

1H-Pyrrolo[2,3-b]pyridin-6-amine features a fused heterocyclic core with a strategically positioned amine group enabling direct functionalization. This scaffold integrates readily into kinase inhibitors and bioactive molecules due to its planar structure and hydrogen-bonding capacity. The compound exhibits favorable solubility in polar solvents and stability under standard bench conditions, facilitating use in medicinal chemistry workflows.

Application

1H-Pyrrolo[2,3-b]pyridin-6-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of kinase inhibitors and other bioactive scaffolds. Its electron-rich pyrrolopyridine core exhibits favorable reactivity in cross-coupling and electrophilic substitution reactions, with excellent bench stability and compatibility with common protecting group strategies.

General Information

CAS No. 145901-11-7
Cat. No. CS-W019627
Purity ≥96%
MDL No. MFCD08272224
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₇N₃
Molecular Weight 133.15
Synonym(s) 6-NITRO-1H-PYRROLO[2,3-B]PYRIDINE
SMILES NC1=CC=C2C(NC=C2)=N1

Computational Chemistry Data

TPSA 54.7
LogP 1.1451
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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1H-Pyrrolo[2,3-b]pyridin-6-amine

CAS No. 145901-11-7

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