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Structure of 145821-55-2
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3-Bromo-1H-pyrrole-2-carboxylic acid integrates a bromine substituent at the C3 position of the pyrrole ring, delivering enhanced reactivity for cross-coupling transformations. The carboxylic acid group enables direct derivatization or salt formation, while the electron-deficient pyrrole core supports efficient functionalization under mild conditions. This compound serves as a key intermediate in the synthesis of bioactive heterocycles and pharmaceutical candidates.
3-Bromo-1H-pyrrole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions to install aryl and heteroaryl substituents at the C3 position. The carboxylic acid group facilitates direct derivatization via amide or ester formation, while the bromine acts as a reliable coupling handle. Its bench-stable solid form and compatibility with standard reaction conditions make it well-suited for iterative synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: