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CS-W001157 4
Total: USD 88.00

4,6-Dichloro-2-(propylthio)pyrimidin-5-amine

  • CAS No. 145783-15-9

  • Cat. No. CS-M1848
  • Purity≥98%
  • MDL No.MFCD16875503

*For research and further manufacturing use only, not for direct human use.

4,6-Dichloro-2-(propylthio)pyrimidin-5-amine|CS-M1848

Structure of 145783-15-9

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General Information

  • CAS No. 145783-15-9
  • Cat. No. CS-M1848
  • Purity ≥98%
  • MDL No. MFCD16875503
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉Cl₂N₃S
  • Molecular Weight 238.14
  • Synonym(s) None
  • SMILES ClC1=C(N)C(Cl)=NC(SCCC)=N1

Synthesis

  • Route1
    • 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine  Ticagrelor Impurity|CS-0167297
      145783-14-8
    • ~99%
    • In-stock
      4,6-Dichloro-2-(propylthio)pyrimidin-5-amine|CS-M1848
      145783-15-9

    References

    • AstraZeneca AB Patent: US2011/71290 A1, 2011 ; Location in patent: Page/Page column 3 ;
  • Route2
    • null|null
      376608-73-0
    • ~%
    • In-stock
      4,6-Dichloro-2-(propylthio)pyrimidin-5-amine|CS-M1848
      145783-15-9

    References

    • WO2005/95358 A2, ; Page/Page column 5-6 ; WO 2005/095358 A2
  • Route3
    • 2-(Propylthio)pyrimidine-4,6-diol  Ticagrelor Impurity|CS-0167261
      145783-12-6
    • ~%
    • In-stock
      4,6-Dichloro-2-(propylthio)pyrimidin-5-amine|CS-M1848
      145783-15-9

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 11 p. 3598 - 3602

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   2.8677
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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