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Methyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate

  • CAS No. 1454848-65-7

  • Cat. No. CS-0043818
  • Molecule weight166.18
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate|CS-0043818

Structure of 1454848-65-7

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General Information

  • CAS No. 1454848-65-7
  • Cat. No. CS-0043818
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) methyl 4H,5H,6H-pyrrolo[1,2-b]pyrazole-2-carboxylate
  • SMILES O=C(C1=NN2C(CCC2)=C1)OC

Description

Methyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate is a heterocyclic scaffold featuring a fused pyrrole-pyrazole core with a pendant methyl ester. This bench-stable, moisture-tolerant compound serves as a key intermediate in the synthesis of bioactive small molecules, particularly where nitrogen-rich ring systems and polar functional groups are required for target engagement.

Application

Methyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. The molecule features a fused pyrrole-pyrazole core with a readily functionalizable ester group, enabling diverse transformations including hydrolysis, reduction, and coupling reactions. Its bench-stable nature and compatibility with common reaction conditions facilitate efficient access to complex scaffolds in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.12
  • LogP   0.6159
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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