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CS-W001157 4
Total: USD 88.00

Methyl carbamimidothioate sulfate

  • CAS No. 14527-26-5

  • Cat. No. CS-0134406
  • Purity≥97%
  • MDL No.MFCD00135509

*For research and further manufacturing use only, not for direct human use.

Methyl carbamimidothioate sulfate|CS-0134406

Structure of 14527-26-5

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General Information

  • CAS No. 14527-26-5
  • Cat. No. CS-0134406
  • Purity ≥97%
  • MDL No. MFCD00135509
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₈N₂O₄S₂
  • Molecular Weight 188.23
  • Synonym(s) None
  • SMILES NC(SC)=N.O=S(O)(O)=O

Description

Methyl carbamimidothioate sulfate delivers a reactive sulfide functionality for nucleophilic substitution, enabling efficient coupling in synthetic pathways. This bench-stable reagent features enhanced solubility in polar solvents and functions as a key intermediate in the construction of heterocyclic systems and functionalized amine derivatives under mild conditions.

Application

Methyl carbamimidothioate sulfate serves as a versatile intermediate in the synthesis of thiourea derivatives and heterocyclic scaffolds. Its reactive thiocarbamoyl group enables efficient coupling with electrophiles, while the sulfate counterion enhances solubility and stability in polar solvents. The compound facilitates straightforward functionalization in multistep sequences and is compatible with standard purification techniques, making it well-suited for bench-scale applications in medicinal chemistry and agrochemical development.

Synthesis

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      Methyl carbamimidothioate sulfate|CS-0134406
      14527-26-5

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 8 p. 2426 - 2431
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      Methyl carbamimidothioate sulfate|CS-0134406
      14527-26-5

    References

    • Journal of the Chemical Society, , vol. 111, p. 650 Journal of the Chemical Society, , vol. 117, p. 6

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   124.47
  • LogP   -0.40993
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   0

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