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CS-W001157 4
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Carboxyl diazirine alkyne

  • CAS No. 1450754-37-6

  • Cat. No. CS-0111747
  • Purity≥98%
  • MDL No.MFCD31433997

*For research and further manufacturing use only, not for direct human use.

Carboxyl diazirine alkyne|CS-0111747

Structure of 1450754-37-6

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General Information

  • CAS No. 1450754-37-6
  • Cat. No. CS-0111747
  • Purity ≥98%
  • MDL No. MFCD31433997
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) None
  • SMILES O=C(O)CCC1(CCC#C)N=N1

Application

Carboxyl diazirine alkyne serves as a versatile bifunctional building block for click chemistry and photoaffinity labeling. The alkyne moiety enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the carboxyl-diazirine group undergoes photoinduced insertion into C–H, N–H, or O–H bonds. This dual functionality facilitates site-specific conjugation in complex molecular architectures, including peptides and small-molecule probes, with excellent bench stability and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 3224
Class : 4.1
Packing Group : -
Hazard Statements : H242
Precautionary Statements : P210-P234-P235-P240-P370+P378-P403

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Computational Chemistry Data

  • TPSA   62.02
  • LogP   1.4267
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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