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CS-W001157 4
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4-Chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine

  • CAS No. 1448695-71-3

  • Cat. No. CS-0610247
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine|CS-0610247

Structure of 1448695-71-3

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General Information

  • CAS No. 1448695-71-3
  • Cat. No. CS-0610247
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃ClIN₃
  • Molecular Weight 279.47
  • Synonym(s) None
  • SMILES IC1=CNC2=C(Cl)N=CN=C21

Description

4-Chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine is a halogenated heterocycle featuring complementary reactive sites for cross-coupling and functionalization. The chlorine and iodine substituents enable sequential derivatization under palladium catalysis, while the pyrrolo[3,2-d]pyrimidine core provides a rigid, electron-deficient scaffold ideal for medicinal chemistry and materials applications.

Application

4-Chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. Its orthogonal halogen handles enable sequential cross-coupling reactions, facilitating efficient diversification in medicinal chemistry. The compound exhibits excellent bench stability and compatibility with palladium-catalyzed transformations, making it ideal for late-stage functionalization and library synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.2159
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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