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Structure of 144806-52-0
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4-(Bromomethyl)-2-chloro-1-nitrobenzene features a bromomethyl group flanked by electron-withdrawing chlorine and nitro substituents, enabling selective nucleophilic substitution. This configuration supports efficient coupling in transition-metal-catalyzed reactions, particularly in the synthesis of functionalized aromatic scaffolds for medicinal chemistry and materials science applications.
4-(Bromomethyl)-2-chloro-1-nitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient C–C and C–heteroatom bond formation. The bromomethyl group facilitates nucleophilic substitution reactions under mild conditions, while the ortho-chloro and nitro functionalities provide orthogonal reactivity for downstream functionalization. Its bench-stable nature and compatibility with standard coupling protocols make it well-suited for modular synthesis of complex aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: