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Structure of 14473-90-6
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(E)-3-(3-Chlorophenyl)acrylic acid features a conjugated enone system with a para-chloro substituent that enhances electron-withdrawing character. This configuration imparts stability and facilitates participation in Michael additions, Diels-Alder reactions, and transition-metal-catalyzed couplings. The planar geometry supports efficient π-stacking in solid-state applications.
(E)-3-(3-Chlorophenyl)acrylic acid serves as a versatile building block for synthesizing biologically relevant α,β-unsaturated carboxylic acids. Its conjugated system enables reliable participation in Michael additions, Diels-Alder reactions, and palladium-catalyzed couplings. The ortho-chloro substituent enhances electrophilic reactivity and provides a handle for further functionalization. Bench-stable and readily purified by recrystallization, it functions effectively in both small-molecule medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352
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Lot numbers can be found on the outside label of a product: