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CS-W001157 4
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4-Hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid

  • CAS No. 1442437-21-9

  • Cat. No. CS-0130938
  • Molecule weight156.10
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid|CS-0130938

Structure of 1442437-21-9

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General Information

  • CAS No. 1442437-21-9
  • Cat. No. CS-0130938
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄N₂O₄
  • Molecular Weight 156.10
  • Synonym(s) 4,6-dihydroxypyridazine-3-carboxylicacid
  • SMILES O=C(C(C(O)=C1)=NNC1=O)O

Description

This dihydropyridazine derivative features a hydroxyl group at C4 and a ketone at C6, paired with a carboxylic acid at C3. The scaffold delivers high functional group compatibility for conjugation, enabling integration into bioactive molecules under standard conditions.

Application

4-Hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling access to pyridazine-based scaffolds relevant in medicinal chemistry. Its orthogonally functionalized core—combining a hydroxyl group, ketone, and carboxylic acid—facilitates diverse transformations including amidation, esterification, and cyclization. The compound exhibits bench stability and compatibility with standard purification techniques, supporting efficient integration into multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   103.28
  • LogP   -0.8263
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   1

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