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CS-W001157 4
Total: USD 88.00

2,3-Dihydrofuro[2,3-b]pyridin-3-ol

  • CAS No. 144186-57-2

  • Cat. No. CS-0187924
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydrofuro[2,3-b]pyridin-3-ol|CS-0187924

Structure of 144186-57-2

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General Information

  • CAS No. 144186-57-2
  • Cat. No. CS-0187924
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₂
  • Molecular Weight 137.14
  • Synonym(s) Furo[2,3-b]pyridin-3-ol, 2,3-dihydro- (9CI)
  • SMILES C1=CC2=C(N=C1)OCC2O

Description

2,3-Dihydrofuro[2,3-b]pyridin-3-ol delivers a fused heterocyclic scaffold with a phenolic hydroxyl group enabling direct derivatization. This bench-stable, moisture-tolerant core integrates readily into synthetic routes for bioactive molecule development, offering enhanced solubility and structural rigidity in medicinal chemistry applications.

Application

2,3-Dihydrofuro[2,3-b]pyridin-3-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to fused bicyclic scaffolds. Its phenolic hydroxyl group provides a site for derivatization, while the dihydrofuran ring imparts structural rigidity and favorable pharmacophoric properties. The compound exhibits good bench stability and compatibility with standard coupling reactions, facilitating its use in lead optimization campaigns and library synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   42.35
  • LogP   0.5074
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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